Characterising RNA secondary structure space using information entropy
نویسندگان
چکیده
منابع مشابه
RNA Secondary Structure Prediction Using Hierarchical Folding
Algorithms for prediction of RNA secondary structure— the set of base pairsthat form when an RNA molecule folds— are valuable to biologists who aim tounderstand RNA structure and function. Improving the accuracy and efficiencyof prediction methods is an ongoing challenge, particularly for pseudoknottedsecondary structures, in which base pairs overlap. This challenge is biologica...
متن کاملRNA secondary structure design.
We consider the inverse-folding problem for RNA secondary structures: for a given (pseudo-knot-free) secondary structure we want to find a sequence that has a certain structure as its ground state. If such a sequence exists, the structure is called designable. We have implemented a branch-and-bound algorithm that is able to do an exhaustive search within the sequence space, i.e., gives an exact...
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In this unit, protocols are provided for predicting RNA secondary structure with the user-friendly RNAstructure desktop computer program and the RNAstructure Web server. The minimum free energy structure and a set of suboptimal structures with similar free energies are predicted. Prediction of high-affinity oligonucleotide binding sites to a structured RNA target is also presented. © 2016 by Jo...
متن کاملRna Secondary Structure Prediction
Understanding secondary structures of RNAs helps to determine their chemical and biological properties. Only a small number of RNA structures have been determined currently since such structure determination experiments are timeconsuming and expensive. As a result, scientists start to rely on RNA secondary structure prediction. Unlike protein structure prediction, predicting RNA secondary struc...
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Non-coding RNAs (ncRNAs) are under intensive research focus since several years ago. Whereas many researches have done in this field since [1], not so much knowledge about ncRNAs are gained so far. One of the reasons for this is that there is not enough computational tools available for ncRNA analysis. ncRNA finding is one of the most important tools for the analysis. However, no viable solutio...
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ژورنال
عنوان ژورنال: BMC Bioinformatics
سال: 2013
ISSN: 1471-2105
DOI: 10.1186/1471-2105-14-s2-s22